Treatment of HIV-1 with Reverse Transcriptase Inhibitors (RTI'S) and Protease Inhibitors (PI'S)

Chirove, Faraimunashe (2005) Treatment of HIV-1 with Reverse Transcriptase Inhibitors (RTI'S) and Protease Inhibitors (PI'S). Masters thesis, University of Zimbabwe.

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Abstract

Treatment with antiretroviral drugs has been reported to delay progression of HIV infection to AIDS, and may even lower the infectiousness of the infectives. This study investigates the effects of treatment of HIV-1 with Reverse Transcriptase Inhibitors (RTI's) and Protease Inhibitors (PI's) at cellular level. A threshold parameter, Ncrit, which determines the outcome of the infection is established. If NT < Ncrit, the infection dies out, while if Ncrit < NT , the infection persists where NT is the number of virions produced by each infected CD4+

Item Type: Thesis (Masters)
Subjects: Q Science > Q Science (General)
Q Science > QA Mathematics
Divisions: Africana
Depositing User: Geoffrey Obatsa
Date Deposited: 27 Nov 2017 14:31
Last Modified: 27 Nov 2017 14:31
URI: http://thesisbank.jhia.ac.ke/id/eprint/2792

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