Esetemariam, Abraham (2013) Polymer Translocation through Nanochannel: - A Two-Dimensional Monte Carlo Simulation Study. Masters thesis, Addis Ababa University.
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Abstract
In this paper we investigate Monte Carlo(MC) simulation of polymer translocation through a nanochannel. To this end we used the Bond Fluctuation Method (BFM) to study the translocation process of a polymer chain of length N in two dimensions, in the absence of external force on the polymer (i.e. unbiased translocation). To overcome the entropic barrier we consider a polymer, in which the center monomer is initially placed in the middle of the channel and study the escape time τ needed for the polymer to completely exit the channel on either side of the end. Numerically we find that the escape time τ scales with the chain length N as τ ∼ N1+2ν , where ν is the Flory exponent as far as the channel is small enough. And this scaling preferably agree with the translocation time of a polymer which passes through a nanopore in one direction only. In this work, we examine the interplay between the channel length L, width W and other parameters while simulating the translocation process.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Nanochannel, Translocation time, Escape time, DNA sequencing |
| Subjects: | Q Science > Q Science (General) Q Science > QC Physics T Technology > T Technology (General) |
| Divisions: | Africana |
| Depositing User: | Selom Ghislain |
| Date Deposited: | 18 Jun 2018 09:51 |
| Last Modified: | 18 Jun 2018 09:51 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/4347 |
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