Prevalence of ARV Related Adverse Drug Reactions among Children Taking HAART at Tikur Anbessa Specialized Hospital

Yitbarek, Aklilu (2010) Prevalence of ARV Related Adverse Drug Reactions among Children Taking HAART at Tikur Anbessa Specialized Hospital. Masters thesis, Addis Ababa University.

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Abstract

Antiretroviral Treatment (ART), although not a cure, can help people from becoming ill for many years and this has improved the survival of HIV patients. In Ethiopia about 55,000 people and globally more than 1.3 million people have been taking ART until the end of 2006. Scaling up of ART treatment is planned by WHO and the Ministry of Health of the Ethiopian Government. Although ART treatment has decreased HIV associated mortality and morbidity, a number of patients still die after the start of ART. A total of 213 child patients have been considered from Tikur Anbessa Specialized Hospital ART clinic for the study. The analysis of the data using the binary logistic regression shows that AZT associated anemia, d4T associated peripheral neuropathy and NVP associated skin rash have influence on the survival of child patients. i.e. Child HIV patients under ART follow up has developed AZT associated anemia, D4T peripheral neuropathy and NVP associated skin rash. The study shows that adverse drug reaction has relation with Base Line Weight, Base Line CD4 Counts, WHO clinical stage, ART regimen and age.

Item Type:	Thesis (Masters)
Subjects:	H Social Sciences > HA Statistics R Medicine > RA Public aspects of medicine R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
Divisions:	Africana
Depositing User:	Selom Ghislain
Date Deposited:	26 Jun 2018 08:55
Last Modified:	26 Jun 2018 08:55
URI:	http://thesisbank.jhia.ac.ke/id/eprint/4568

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