Basha, Chekesa (2012) Antibacterial Activity of Moringa stenopetala against some Human Pathogenic Bacterial Strains. Masters thesis, Addis Ababa University.
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Abstract
An emerging of antibiotic resistance brings most serious public health problems. It is therefore, important to look for more effective, safer and less toxic alternate options of treatment. The aim of the present study was to investigate antibacterial activity of Moringa stenopetala against some human pathogenic bacteria using disk diffusion method and agar dilution for minimum inhibitory concentration. The result revealed that, most of the plant extracts had antibacterial activity. Staphylococcus aureus was found to be the most susceptible bacteria to crude 80% methanol extract of seeds and ethyl acetate extract of root barks with inhibition zones of 18.66±0.88mm and 16.00±1.15mm and minimum inhibitory concentration of 1.25mg/ml and 2.5mg/ml respectively, whereas Pseudomonas aeruginosa was the most resistant bacteria to all of crude extracts. Similarly, Staphylococcus aureus was the most susceptible bacterial strain to chloroform fraction with inhibition diameter of 28.00±0.57mm and minimum inhibitory concentration of 0.31mg/ml, while Pseudomonas aeruginosa was the most resistant strain with inhibition zone of 9.66±0.33mm and minimum inhibitory concentration of10mg/ml respectively. In conclusion, this study is not only proves antibacterial activity of Moringa stenopetala, also provides a scientific basis for their traditional use. Pure chemical compounds and antimicrobial activity against many fungi and bacteria should be studied to use them as sources and templates for synthesis of drugs to control infectious diseases.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Antibacterial activity, Moringa stenopetala, traditional medicine, extracts, fractionation, MIC, solvents |
| Subjects: | Q Science > Q Science (General) Q Science > QH Natural history > QH301 Biology Q Science > QK Botany Q Science > QR Microbiology Q Science > QR Microbiology > QR180 Immunology R Medicine > RA Public aspects of medicine R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RV Botanic, Thomsonian, and eclectic medicine |
| Divisions: | Africana |
| Depositing User: | Selom Ghislain |
| Date Deposited: | 11 Sep 2018 07:45 |
| Last Modified: | 11 Sep 2018 07:45 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/5102 |
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