Aklilu, Addis (2016) Bacterial and Fungal Pathogens from External Ocular Infection at St. Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia. Masters thesis, Addis Ababa University.
![[img]](http://thesisbank.jhia.ac.ke/style/images/fileicons/application_pdf.png) |
PDF (Bacterial and Fungal Pathogens from External Ocular Infection at St. Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia)
Addis Aklilu.pdf - Published Version Restricted to Repository staff only Download (740kB) | Request a copy |
Abstract
Background:-Ocular infection is a major public health problem in developing countries. Bacteria and fungi associated with external ocular infection are responsible for increased incidence of morbidity and blindness worldwide. Objective:-The aim of this study was to determine the profile of bacterial and fungal pathogens from external ocular infection at St. Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia. Methodology:-A cross sectional study conducted using convenient sampling technique. A total of 215 patients recruited from April to August, 2016. Conjunctival and eyelid margin swabs and corneal scraping were collected. Demographic data were collected using structured questionnaire. All Specimens were processed for microbiological analysis as per standard procedures and antibiotic susceptibility test was done using disc diffusion technique. The data was analyzed by using SPSS version 20 and appropriate statistical tools were used. Result: - A total of 215 patients were enrolled in this study. Of which 133(61.4 %) were culture positive. Of this 118(54.9%) and 24(11.2%) were bacterial and fungal pathogens respectively. There were 9 (6.8%) bacterial and fungal co-infections. Majority were males 109 (50.7%). The mean age of the study participants was 42.34 (Sd. +20.55) and majority of participants age were within the age range of 25-44 years 72(33.5%). Majority had conjunctivitis 87(40.5%) followed by blepharitis 48(22.3%). The predominant bacterial pathogen isolated were gram positives 88(74.6%). Of this S. aureus 32(27.1%) was the commonest isolate and K. pneumoniae 9(7.6%) was the predominant from gram negative bacterial pathogens. Aspergillus species 14(58.3%) were the most predominant fungal isolates. Gram positive cocci and gram negative rods were highly resistant for Penicillin 66/88(75%) and Ampicilin 20/27(81.5%) respectively. 71.2% of MDR bacteria were isolated. There was statistically significant association between prevalence of bacterial isolates and age variation (P=0.023) and trauma with fungi prevalence (P=0.002). Conclusion:-The prevalence of bacterial and fungal pathogens was higher among external ocular infection. The drug resistance among ocular bacterial infection was also higher.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | External ocular infections, conjunctivitis, blepharitis, keratitis, dacryocystitis, susceptibility |
| Subjects: | Q Science > Q Science (General) R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 27 Jun 2018 07:30 |
| Last Modified: | 27 Jun 2018 07:30 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/5957 |
Actions (login required)
 |
View Item |