Assessment of Extent of Contact Tracing for Multi Drug Resistant Tuberculosis in St. Peter Tuberculosis Specialized Hospital Addis Ababa, Ethiopia

Titiyos, Addisalem (2013) Assessment of Extent of Contact Tracing for Multi Drug Resistant Tuberculosis in St. Peter Tuberculosis Specialized Hospital Addis Ababa, Ethiopia. Masters thesis, Addis Ababa University.

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Abstract

Background: MDR-TB like pulmonary tuberculosis is transmitted through air droplets from infected person, highly potential to spread with in people who have close contact. Contact tracing for index cases with multidrug-resistant TB (MDR-TB) or extensively drug-resistant TB (XDR-TB) is an urgent priority. Close contacts of TB cases, such as household members, are the most likely to become infected, and due to intense and/or prolonged exposure to index cases in the weeks to months before diagnosis and treatment initiation. In Ethiopia an estimated 5200 MDR TB cases emerged in 2008; an estimated 1,600 MDR-TB cases are notified among new pulmonary TB cases in 2010. Objective: to assess extent of contact tracing for multidrug resistance tuberculosis in St. Peter tuberculosis specialized hospital Methodology: A quantitative cross sectional study design was applied to assess the extent of contact tracing for multi drug resistance tuberculosis cases in St. Peter Tuberculosis specialized hospital from October to December 2012, The records of all confirmed MDR TB cases since 2009 were reviewed using secondary data from Tb register and patient files at the MDR TB centers. The data presented in terms of frequency, mean/median value for continuous data and percentage for categorical data and bivariate and multivariate analysis were used to determine and identify factors associated with contacts of MDR TB cases. Result: A total of 508 index case were identified from MDR TB care unit registry, from these index cases 29 (5.7%) traced. A total of 16 confirmed contacts of MDR TB cases were identified from the total 29 index household and from the sixteen confirmed MDR TB contact cases (13) 81.25% were also diagnosed for pulmonary TB. The odds of contacts from Addis Ababa five times higher compared to the odds of contacts out of Addis Ababa [OR: 5, 95% C.I: 1.03, 24.28]. Conclusion: The study described high proportion of MDR TB among contacts. Findings demonstrate that close contacts of MDR-TB were at higher risk for MDR TB and pulmonary TB. The findings suggest that enhanced contact tracing in MDR-TB contacts.

Item Type: Thesis (Masters)
Subjects: Q Science > QR Microbiology
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Africana
Depositing User: Vincent Mpoza
Date Deposited: 27 Jun 2018 07:36
Last Modified: 27 Jun 2018 07:36
URI: http://thesisbank.jhia.ac.ke/id/eprint/5961

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