Kemal, Ahmed (2014) Prevalence of H.Pylori Infection in Pediatric Patients who is Clinically Diagnosed for Gastroenteritis in Beham Specialized Children S Higher Clinic, Addis Ababa, Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
Background: The public health impact of Helicobacter pylori (HP) infection is gradually becoming obvious, the bacterium now being implicated as an aetiologic agent in a variety of gastric diseases. In developing countries, Hp infection is markedly more prevalent at younger ages than in developed countries. According to World Gastroenterology Organisation (WGO) 2010 the prevalence of HP in Ethiopia was 48% in age between 2 4, 80% at the age of 6 and 95% in adult s population. Objective: To determine the prevalence of H.pylori infection among paediatric patients who s clinically diagnosed for gastroenteritis. Method: A cross sectional study was conducted to determine the prevalence of H.pylori infection among pediatric patient in private pediatric clinic, Addis Ababa Ethiopia. The study was conduct from March 3rd to May 11th 2014. Non-probability convenient sampling technique was used to collect the data. The stool samples were tested according to the manufacture instruction and procedure. Information from the laboratory analysis and questionnaires were entered into SPSS, version.17 and odd ratio, 95%CI were calculated to measure the degree of relationship between risk factors for H. pylori infection. Result: A total of two hundred twenty one paediatric patients having upper gastrointestinal symptoms because of a suspicion of H. pylori infection participated in this prospective study at Beham specialized children s higher clinic between March 2014 and May 2014.Among the study subjects 114(51.6%) were girls and 107 (48.4%) were boys aged from 9months to 15years with the mean age of 6.29 [95% CI 5.9-6.7]. Helicobacter pylori antigens were detected in 57 of the 221children giving an overall prevalence of 25.8% (95%CI 18.8-31), 27.2% in female and 24.3% in male children. The frequency of H. pylori colonization was higher in females than in males. Of the 114 females enrolled in the study, H. pylori antigen was detected in the stools of 31 (27.2%) against 26 (24.3%) of the 107 males (OR = 0.85 95%CI=0.46-1.57). Age of acquisition was one year and five month. Conclusions: The prevalence of H. pylori infection is 25.8%. This is high among children in the study area. Infection also is acquired at very early age. Household crowding is one of the factors that enhance the infection.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | Q Science > Q Science (General) R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 27 Jun 2018 12:03 |
| Last Modified: | 27 Jun 2018 12:03 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/6029 |
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