Denekew, Alem (2014) Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting and Affecting Factors among Health Care Providers Working in ART Clinics of Public Health Facilities in Addis Ababa City, Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
New adverse events and toxicities are identified as people live longer on ART and the availability of numerous new drugs and drug combinations make systematic monitoring of ADR critical in the HIV program. The contribution of health professionals to adverse drug reaction databases is enormously significant, but under-reporting remains a major draw-back of spontaneous reporting and the level of adverse drug reaction reporting in Ethiopia is alarmingly low. Thus, a facility based cross sectional study was conducted in ART clinics of public health facilities of Addis Ababa city to assess the health care providers’ knowledge, attitude & practice on adverse drug reaction reporting. A total of 250 health care providers were included in the study by considering a 10% nonresponse rate. Using proportional allocation to type of facilities; 9 facilities from Public hospitals and 27 from health center based ART clinics were selected. Data was collected through a selfadministered questionnaire from health professionals selected by simple random sampling methods. Observation was also used to verify existence of reporting forms in the facilities. After the data collection was completed, data was entered and processed using EPI-info software and exported to SPSS for analysis. The response rate was 93.22%. Among respondents (108)46.2% were aware of the existence of a national Pharmacovigilance center in Ethiopia and only 92(39.3%) of them knew where it is located. Among the respondents only 134(57.3 %) of them were aware of the yellow card reporting scheme for reporting ADRs. Most respondents 208 (88.9%) agree the fact that ADR should be reported spontaneously at a regular basis. 212(92.7%) of them also agree that reporting ADR is part of their duty as health professionals & 197(84.2%) of the respondents believe that reporting ADR should be mandatory. 101 (43. 2%) of the respondents encountered at least one patient on ADR in their clinical practice in the past one year and 96(41%) of the respondents encountered at least one ADR on PLWHAs taking ART. But only 31(30.7%) of the respondents reported that they noted the ADR they encountered on patient clinical or pharmacy record and only 34(14.5%) of the respondents had ever reported ADRs. The present study revealed the health care professionals have positive attitudes towards ADR monitoring and reporting. But there are gaps in knowledge and practice of ADR reporting. The major reasons for under reporting are found to be concern that the report may be wrong, lack of confidence on diagnosis of ADR and unavailability of reporting forms.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RA Public aspects of medicine > RA1001 Forensic Medicine. Medical jurisprudence. Legal medicine |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 29 Jun 2018 09:19 |
| Last Modified: | 29 Jun 2018 09:19 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/6063 |
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