Gebreweld, Angesom (2015) Hematological Profile of Pregnant Women at St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
Background:In Pregnancy, the hematological system undergoes changes in order to meet the demands of the developing fetus and placenta, with major alterations in blood volume. Hemodilution during pregnancy contribute to majority of these changes.Although physiological in nature, but abnormal hematological profile affect pregnancy and its outcome. Anemia is the most common hematological problem in pregnancy, followed by thrombocytopenia. Objective:To assess hematological profiles of pregnant women at St. Paul‟s Hospital Millennium Medical College. Method:A cross sectional study was conducted on 284 pregnant women to assess hematological profiles of pregnant women at St. Paul‟s Hospital Millennium Medical College from June to August 2014. A pre-tested Structured and interviewer administered questionnaire was used to collect socio demographic data and venous blood was used to perform CBC and peripheral blood film. CBC was done using automated hematological analyzer Cell Dyn 1800. Data was analyzed using SPSS version 16.0statistical software. Dependent variable frequencies, mean, standard deviation and range were calculated. P values <0.05 was considered as statistically significant. Result: The prevalence rates of anemia and thrombocytopenia were 11.62% and 7.7 %, respectively and were dominantly of mild type. The anemic pregnant women had microcytic hypochromic (51.5 %), normocytic hypochromic (27.3%), normocytic normochromic (18.2%), and dimorphic (3%). Gestational age (trimester), second and third trimesters compared to those in first trimester and those whodid not take iron folic/acid supplementation compared to those taking supplementation, were more likely to be anemic. The prevalence of thrombocytopenia was 4.2%, 6.1% and 9.4% at first, second and third trimester pregnant women, respectively. Conclusion:The prevalence of anemia and thrombocytopenia was 11.62% and 7.7 %, respectively and were dominantly of mild type. The commonest type of anemia was microcytic- hypochromic and normocytic- hypochromic, which are mostly characteristic features of iron deficiency anemia. Thrombocytopenia where higher in pregnant women at third trimester. Therefore, the pregnant women screening should include hematological parameters other than Hb determination alone to avoid adverse outcomes.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Pregnant women, Hematological profile, anemia, thrombocytopenia |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) R Medicine > RT Nursing |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 29 Jun 2018 14:13 |
| Last Modified: | 29 Jun 2018 14:13 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/6322 |
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