Assessment of Renal Stone Composition and Associated Risk Factors among Patients Attending Urology Department of St. Paul’s Hospital Millennium Medical College and Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Kibe, Hamelmal (2017) Assessment of Renal Stone Composition and Associated Risk Factors among Patients Attending Urology Department of St. Paul’s Hospital Millennium Medical College and Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Masters thesis, Addis Ababa University.

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Abstract

Background: Urolithiasis or renal stone is a global problem whose incidence is reported to be on the rise across the world. It is a common and a major cause of morbidity worldwide including Ethiopia. Therefore, this study was aimed to increase understanding of the prevalence and risk factors of renal stone in Addis Ababa, Ethiopia. Objective: To evaluate renal stones chemical composition and associated risk factors among patients attending at urology department of St. Paul Hospital Millennium Medical College and Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Method: Across sectional study was conducted at the department of urology, TASH and SPHMMC from January to April 2017. Seventy three adult patients with renal stones who were eligible for inclusion included in this study. Blood, urine and renal stone samples were collected at SPHMMC and TASH. Stones were chemically analyzed for about ten types of renal stone composition. The collected data was entered into excel, cleaned and analyzed using SPSS version 20. Result: During the study period a total of 73 study participants attended urology department at TASH and SPHMMC were included, out of these 52 (71.2) were Males. Male to female ratio was 2.5:1. The age of study subjects having stone was ranging from 20 to 71years. The mean age of the study subjects was 39 (SD 12.5) years. Majority (34.2 %) of the participants were in the age group of 35-44 years. Majority of the calculi were composed of calcium oxalate, phosphate, magnesium, magnesium-phosphate and ammonia. In most cases mixed form of calculi (91.8%) were observed .There was an association between phosphate composition with male sex, urinary pH and occupation with ammonia. Conclusion and recommendation: Stones containing calcium oxalate were predominant across the age groups and in both sexes. Further study on larger sample size is recommended.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Renal calculi, Urolithiasis, Nephrolithiasis, Stone composition, Ethiopia
Subjects: H Social Sciences > HD Industries. Land use. Labor > HD61 Risk Management
Q Science > QD Chemistry
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Africana
Depositing User: Emmanuel Ndorimana
Date Deposited: 02 Jul 2018 10:05
Last Modified: 02 Jul 2018 10:05
URI: http://thesisbank.jhia.ac.ke/id/eprint/6399

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