Mengesha, Hanna (2015) Association of Non Breast Feeding and Breast Cancer among Patients on Chemotherapy and Radiotherapy at Tikur Anbessa Specialized Hospital: A Case-Control Study. Masters thesis, Addis Ababa University.
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Abstract
Background: Breast cancer is a major life-threatening public health problem of great concern, with more than one million cases occurringworldwide annually. In Ethiopia breast cancer is the second most often occurring cancer among women. Even though there were studies that were done on risk factors of breast cancer worldwide there are very few studies in developing country especially in Ethiopia. Clarifying the role of non- breastfeeding in developing breast cancer may be helpful to establish preventive and control program to reduce the occurrence of the disease and serve as a baseline for further studies. Objectives: To assess the association between non breastfeeding practices and breast cancer development among patients who are on chemotherapy or radiotherapy at TikurAnbessa Specialized Hospital. Methods: This is unmatched case-control study design that tried to assess the association between non breast feeding practice and breast cancer. The study wasdone at TikurAnbessa Specialized Hospital radiotherapy center which is located in Addis Ababa, Ethiopia. Eligible cases were female breast cancer positive patient (pathology proven) and the controls were female breast cancer negative patient who were diagnosed for other non-reproductive system cancer, both cases and controls were either on chemotherapy or radiotherapy treatment service at TikurAnbessa Specialized Hospital. Theratio was 1:1 with 217female breast cancer patients and 217 females without breast cancers. The analyses were performed with Statistical Package for Social Sciences (SPSS) version 20. Odds ratio and 95% confidence interval done to quantify association between an exposure and disease. Result: , the odds of cases to report positive family history for breast cancer is about 2.6 times higher than the odds of controls to report the same. [AOR = 2.7(95%CI, 1.53, 4.93)]. The odds of cases to report menopausal status for breast cancer is about 2.4 times higher than the odds of controls to menopausal status to breast cancer. [AOR=2.4 (95% CI(1.2,4.7)]. The odds of cases that breastfed for breast cancer is about 50% lower than the odds of controls to report the same. [AOR = 0.05(95%CI, 0.34, 0.87)] Conclusion: The study document show that family history of breast cancer, women who never breast fed, and women in menopausal status were associated with Breast cancer risk. An inverse association between breastfeeding and breast cancer was found in this study among women on chemotherapy and radiotherapy in TikurAnbessa Hospital.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Emmanuel Ndorimana |
| Date Deposited: | 02 Jul 2018 13:05 |
| Last Modified: | 02 Jul 2018 13:05 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/6419 |
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