Adato, Ayele (2015) Prevalence and Associated Risk Factors of Hepatitis B and Hepatitis C Virus among Volunteer Blood Donors in Arbaminch Blood Bank. Masters thesis, Addis Ababa University.
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PDF (Prevalence and Associated Risk Factors of Hepatitis B and Hepatitis C Virus among Volunteer Blood Donors in Arbaminch Blood Bank)
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Abstract
Background: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) is major public health problems that affect million people worldwide and people who are infected assumed to develop liver cirrhosis or hepatocelular carcinoma. Infected peoples are at latent stage before clinical sign and symptom, screening of blood donors is very important for healthy and safe blood donation. Objective: To assess prevalence and associated risk factor of HBV and HCV among volunteer blood donors in Arbaminch blood bank. Method: A cross sectional study design was conducted among blood donors in Arbaminch blood bank from Feb 2015-Aug 2015. A total of 359 volunteer blood donors who came to Arbaminch blood Bank were interviewed face to face, then data was collected by using structured and pretested questionnaire, and finally blood sample drown and tested for HBV and HCV by using ELISA (enzyme linked immunosorbent assay) technique. Descriptive statistics was calculated for most variables in the study. OR and 95% CI was used to assess the association. Result: Prevalence of HBV and HCV among study participant was 4.7% and 0% respectively. From 17 participants tested positive for HBV, 8 (47%) were males. The test positivity among male was 8/197 (4.1%) while among females was 9/162 (5.6%) and more than three forth participants tested positive were age less than 25. After multivariate analysis, when positivity was compared among study participants grouped based on average monthly income, participants earning 581-1,300 were 32.2% less likely to have infection than participants earning below 580 birr per month. (AOR= 0.322, 95%CI =0.108-0.961). Volunteer donors who exposed to unsafe therapeutic drug injection was 8(2.2%) and from those 3(37.5%) was positive for HBV. When compare to volunteers who did not exposed 14(4%), exposed donors 11 times increased risk of HBV infection. This was statistically significant (AOR=11.090, p=2.258-54.475). Conclusion: Prevalence HBV of among volunteer blood donors in Arbaminch Blood Bank was 4.7%. Low monthly income and using unsafe therapeutic injection were related to HBV infection. Recommendation: Improve community awareness, infection control and post counseling will be done to control infection.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | hepatitis B virus, hepatitis C virus, volunteer blood donor |
| Subjects: | Q Science > Q Science (General) Q Science > QR Microbiology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 03 Jul 2018 07:51 |
| Last Modified: | 03 Jul 2018 07:51 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/6482 |
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