Level of Adherence and Associated Factors to Option B+ PMTCT Programme among Pregnant & Lactating Mothers in Selected Government Health Facilities of South Wollo Zone, Amhara Region, North East Ethiopia, 2016

Tsegaye, Delelegn (2016) Level of Adherence and Associated Factors to Option B+ PMTCT Programme among Pregnant & Lactating Mothers in Selected Government Health Facilities of South Wollo Zone, Amhara Region, North East Ethiopia, 2016. Masters thesis, Addis Ababa University.

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Abstract

Introduction፡ Adherence to ART among HIV positive pregnant & lactating mothers is a central component in PMTCT to reduce viral loads & achieve elimination of mother to child transmission of HIV. Option B+ PMTCT programme is a recently introduced approach to eliminate new HIV infection among children. This approach is based on treatment as prevention to mean starting lifelong ART for all HIV positive pregnant & lactating mothers without considering CD4 count or clinical stage of HIV/AIDS disease. Objectives: The aim of this study was to measure the level of adherence and identify factors associated with adherence to option B+ PMTCT programme among pregnant & lactating mothers in selected government health facilities of south wollo zone, Amhara region, north east Ethiopia Method: An institution based cross sectional quantitative study design was used. The study was conducted in two hospitals & five health centers found in south Wollo zone, Amhara region. The sample size required for this study was 191 HIV+ pregnant & lactating mothers who were on PMTCT follow up. The study subjects were taken consecutively until the sample size was met from March 1 to April 14, 2016. Standard structured data collection instrument was used & it was collected by using face to face interviewing. The data were entered in to EpiData 3.1 then exported to statistical package for social science (SPSS) window version 21 for analysis. Entered data were explored for errors & missing values then it was cleaned before analysis. Bivariate and multivariate logistic regression analyses were employed to identify associated factors for adherence. P-value less than 0.05 with 95 % confidence interval was used to state the association between independent predictors and the outcome variable. Result: A total of 190 HIV+ pregnant & lactating mothers were included in this study. The level of adherence on option B+ PMTCT drug was 87.9 %. Factors such as those who attend in Hospital(AOR 0.3,95% CI(0.11-0.82), rural residence (AOR 0.26, 95%CI (0.1-0.73) and those who faced challenges in the same day diagnosis of HIV and initiating lifelong option B+ treatment (AOR 0.08, 95%CI (0.02-0.37) were associated factors for adherence Conclusion & recommendation: mothers who attended for option B+ drugs in health centers, those who lived in urban area and who had no any challenges in same day diagnosing & initiating option B+ drugs were significantly associated factors for better adherence to option B+drugs. Therefore, the ability to effectively handle these factors is crucial in the success of option B+ programme.

Item Type: Thesis (Masters)
Uncontrolled Keywords: adherence, Option B+, HIV+ pregnant & lactating mothers, north east Ethiopia
Subjects: Q Science > Q Science (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RT Nursing
Divisions: Africana
Depositing User: Vincent Mpoza
Date Deposited: 17 Oct 2018 14:04
Last Modified: 17 Oct 2018 14:04
URI: http://thesisbank.jhia.ac.ke/id/eprint/6894

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