Sero-Prevalence of Selected Transfusion-Transmitted Pathogen and Associated Risk Factors among Blood Donors at the National Blood Bank Service in Addis Ababa

Assefa, Lulseged (2017) Sero-Prevalence of Selected Transfusion-Transmitted Pathogen and Associated Risk Factors among Blood Donors at the National Blood Bank Service in Addis Ababa. Masters thesis, Addis Ababa University.

PDF (Sero-Prevalence of Selected Transfusion-Transmitted Pathogen and Associated Risk Factors among Blood Donors at the National Blood Bank Service in Addis Ababa) LULSEGED ASSEFA.pdf - Accepted Version Restricted to Repository staff only Download (977kB) | Request a copy

Abstract

Background. Blood donation saves millions of lives. Although blood transfusion plays an important role in the supportive care of medical and surgical patients, unsafe transfusion practices also put millions of people at risk of transfusion-transmitted infections (TTIs). OBJECTIVES: To determine the seroprevalence of HIV, HBV, HCV and syphilis among prospective blood donors in National Blood Bank Service. Materials and methods: A cross sectional prospective study was conducted among volunteer blood donors in National Blood Bank Service; from February 2016 to June 2016 and sociodemographic information about the donors was obtained by interview using a structured questionnaire. RESULTS: A total of 1576 blood donors were screened during the study period. And among them a vast majority 1110, (70.5%) were male and 466 (29.5%) were female. All blood donors were volunteers. 33 of them were housewives, 972 employed, 325 students and 246 daily laborers. Majority of the donors belong to the age group of 18-30 years.(988 or 62.7%) followed by the age group of 31-40 years (431 or 27.3%). The mean age was 29.42 years.The overall prevalence of TTIS was 84 (5.3%). of which 18 (1.1%)consist of HIV ,HBV 43 (2.7%),HCV 1 (0.06%),Syphilis 22 (1.4%).The prevalence of HBsAg was the highest followed by Syphilis, HIV, HCV. out of total 84 positive samples. Conclusion: The prevalence of transfusion transmissible infection in this study is relatively low 84 (5.3%) compared to earlier years when blood banks used to collect blood from all types of donors (including replacement and professional donors). However, compared to settings similar to this study, the prevalence of the four infections observed in this study calls for more efforts in order to reduce the burden of the infections among the general population.

Item Type:	Thesis (Masters)
Subjects:	Q Science > QR Microbiology Q Science > QR Microbiology > QR180 Immunology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions:	Africana
Depositing User:	Emmanuel Ndorimana
Date Deposited:	17 Oct 2018 13:22
Last Modified:	17 Oct 2018 13:22
URI:	http://thesisbank.jhia.ac.ke/id/eprint/6934

Actions (login required)

View Item