Review of Histologic Results of Vaginal Hysterectomy Specimens Done for Pelvic Organ Prolapse: 4 Year Retrospective Cross Sectional Study

Ayichew, Zelalem (2014) Review of Histologic Results of Vaginal Hysterectomy Specimens Done for Pelvic Organ Prolapse: 4 Year Retrospective Cross Sectional Study. Masters thesis, Addis Ababa University.

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Abstract

Back ground: Pelvic organ prolapse is a health concern affecting millions of women worldwide. It can severely affect a woman’s quality of life by limiting physical, social, psychological and sexual function. Significant numbers of women in Ethiopia are also suffering from such problem, even at the young age. Vaginal hysterectomy with pelvic floor repair is one of the frequently performed surgeries in treating women who have completed their family and are not particular about preserving menstrual function. It is a routine practice to send all these hysterectomy specimens for further histopathologic analysis, to look for the presence of incidental pathologic findings. But routine pathologic examination is inappropriately time consuming, costly, and contributes little if anything to the further management of the patient. This study aims to review the histologic results of vaginal hysterectomy specimens done for POP. Objectives: The aim of this study was to review the histologic results of vaginal hysterectomy specimens done for pelvic organ prolapse. Methods: A facility based cross sectional study was done to review the histologic results of vaginal hysterectomy specimens that are done only for uterovaginal prolapse. The study was conducted in Tikur Anbesa Specilized Hospital, Department of Pathology. Four years (Sept 2009 - Sept 2013) computer saved data and patients medical records were used to analyze the result. The data was entered, cleaned, and analyzed using SPSS 17.0 statistical software. Results: Out of the 306 vaginal hysterectomy specimens, histologic analysis was done to all of the cervical tissues (100%). But histological analysis done only to 4 (1.3%) and 7 (1.9%) of the myometrial and the endometrial tissues respectively, because, according to the protocol of the Department of Pathology, tissues other than the cervix will undergo histologic analysis only if they are found to be abnormal on gross examination. Out of the 306 specimens, only 10(3.2%) show abnormalities on gross examination. On histologic examination, including the cervix, 40(13.1%) of the specimens had pathologic findings of which only 4(1.3%) were clinically significant, all of which were precancerous cervical lesions, the rest were benign lesions. Conclusion and recommendation: The proportion of histologically analyzed parts of the specimen subjected is very low which probably resulted in the reduction in the incidence of overall incidental pathologic abnormalities in this study. Appropriate and complete histologic evaluation of each part of the specimens should be undertaken to get a base line data and help make decisions in the future whether subjecting specimen for routine histopathological analysis after vaginal hysterectomy should be practiced or not.

Item Type: Thesis (Masters)
Subjects: R Medicine > RG Gynecology and obstetrics
Divisions: Africana
Depositing User: Vincent Mpoza
Date Deposited: 24 Oct 2018 08:13
Last Modified: 24 Oct 2018 08:13
URI: http://thesisbank.jhia.ac.ke/id/eprint/6995

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