Damtew, Emeshaw (2014) Prevalence of Diabetes Mellitus among Active Pulmonary Tuberculosis Patients at St. Peter Specialized Hospital, Addis Ababa Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
Background: The merging epidemics of pulmonary tuberculosis (PTB) and diabetes mellitus (DM) have been raised concerns by many experts but no large scale screening and intervention have been launched yet, especially in low-income countries like Ethiopia. The thought that tuberculosis could cause diabetes seems farfetched, but is not. The peculiar relationship and frequent association of diabetes mellitus and tuberculosis has been observed for more than 2000 years, yet the reason for this correlation is, to this day, not known. Objective: the aim of this study was to determine the prevalence of diabetes mellitus among active PTB patients at St.Peter hospital. Methods/design: A cross-sectional Hospital based study was carried out and the study included all active pulmonary tuberculosis patients visiting St. Peter specialized hospital until the required sample size was obtained. We included 120 active PTB patients: 67 of these were male and 84 of them were urban dwellers. Analysis of fasting blod glucose was carried out using venous blood samples by enzymatic colorimetric test for glucose (GOD-PAP Method). For testing significance, the categorical data were compared using a chi-square test and expressed as proportion with a 95% confidence interval. Result: The prevalence of DM was found to be 15.8% (95% CI:9.20-22.45), which was higher (25.4%) among male than female TB patients(3.8%).Likewise 70% of the patients were from urban and 30% of them were from rural areas. The prevalence of newly diagnosed diabetic cases was 84.2% of all patients tested positive for DM. And all of the patients diagnosed as diabetic were in the age group greater than 25 years of age. The prevalence of IFG was (26.7%) and that of HIV co-infection in the study population was (52.5%). The occurrence of DM in HIV co-infection was a little bit higher (15.9%) than HIV negative TB patients (15.8%). Of all patients with active tuberculosis, 60 (50%) were sputum smear negative. The proportion of DM was (25%) among smear positive and (6.7%) among smear negative patients. Conclusion: The prevalence of diabetes mellitus and pre-diabetes (IFG) among active pulmonary tuberculosis cases was higher compared to the published prevalence of DM in Ethiopia. Therefore, it is important to implement a screening program of each TB patient for diabetes and Vis versa.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | TB/DM, IFG, HIV co-infection |
| Subjects: | Q Science > QR Microbiology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 24 Oct 2018 08:51 |
| Last Modified: | 24 Oct 2018 08:51 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/7040 |
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