Prevalence of Transfusion Transmitted Infections among Blood Donors at Yirgalem Hospital and Hawassa Blood Bank Center, Sidama Zone, SNNPRS, Ethiopia

Bonja, Fisseha (2015) Prevalence of Transfusion Transmitted Infections among Blood Donors at Yirgalem Hospital and Hawassa Blood Bank Center, Sidama Zone, SNNPRS, Ethiopia. Masters thesis, Addis Ababa University.

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Abstract

Blood is one of the integral components of body constituents. Blood transfusion is important therapy during maternal bleeding, surgery and also a lifesaving procedure for anemic patients. Transfusion reaction and transfusion transmitted infections (TTI) are major problems associated with blood transfusion. TTI is ranging from 8% up to 43%. The burden of transfusion transmitted infections in developed countries decline from time to time but it is still a challenge of developing countries like Ethiopia due to lack of adequate volunteer donors, testing material, good infrastructure and well trend personnel because of resource constraints. In addition to that there are insufficient data on seropostivity of TTI among blood donors in our setting. Objective To assess the prevalence of transfusion transmitted infections among blood donors at Yirgalem hospital blood bank and Hawassa blood bank center, Sidama zone, SNNPRS Ethiopia. Methodology Institutional based cross-sectional study was conducted, convenient sampling techniques used to address 384 donors and blood collection was done from health volunteers and replacement donors from April-May, 2015 G.C at Yirgalem Hospital and Hawassa regional Blood bank. Data was coded, cleaned, entered and analyzed by using SPSS version 21.Proportion, odds ratio and p-value were used for analyses. P-value <0.05 considered as statistically significant. Result A total of 384 blood donors were screened and the overall prevalence of TTI was 28 (7.29%). The Seroprevalence of HIV, HBV, HCV, Syphilis and Malaria was 6(1.6%), 16(4.2%), 2(0.5%), 3(0.8%) 1(0.3%) respectively. Two out of 384(0.5%) had multiple infections. The combinations were HIV-HBV 1/384(0.26%) and HIV-HCV1/384(0.26%). The prevalence of HBV was 13/258(5.0%) and 3/126(2.4%) in male and female respectively, p=0.001. When see the age of donors, 15/331(4.5%) and 1/41(2.4%) in age group18-24 and 25-34 years respectively. The prevalence of HIV was 1/25(4.0%) and 5/359(1.4%) in urban and rural respectively, p=0.002 Conclusion and Recommendation The prevalence of TTI was 28(7.29%), the seroprevalence of HIV 6(1.6%), HBV 16(4.2%), HCV2 (0.5%), Syphilis 3(0.8%) and Malaria 1(0.3%). High prevalence of HBV, HCV and syphilis infection were found among family replacement blood donors when compared with voluntary blood donors. Students highly participated in voluntary blood donation program when compared with others. Creating awareness among the public is important to have voluntary donors and this helps to provide safe blood to blood transfusion and collection services.

Item Type:	Thesis (Masters)
Subjects:	Q Science > Q Science (General) Q Science > QR Microbiology > QR180 Immunology
Divisions:	Africana
Depositing User:	Vincent Mpoza
Date Deposited:	11 Jul 2018 12:13
Last Modified:	11 Jul 2018 12:13
URI:	http://thesisbank.jhia.ac.ke/id/eprint/7323

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