Visceral Leishmaniasis in Bira Abo, a Kebele in Addis Zemen: Sero-epidemological and Leishmanin Skin Test Survey

Kebede, Seleshi (2007) Visceral Leishmaniasis in Bira Abo, a Kebele in Addis Zemen: Sero-epidemological and Leishmanin Skin Test Survey. Masters thesis, Addis Ababa University.

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Abstract

Visceral leishmaniasis is a serious public health problem of global importance, with a total of 200 million people at risk, an estimated 500 000 symptomatic new cases each year worldwide. The aim of this study was to determine the prevalence and exposure of Visceral leishmaniasis in Bira Abo kebele, one of the localities in Addis Zemen (Northern Ethiopia) in June 2006.Sero-epidemological and Leishmanin skin test survey of VL was carried out. A total of 1280 subjects comprising 709 males and 571 females and 30 previously treated VL patients were included in the study. After clinical screening, 1280 sera were tested by Direct Agglutination Test (DAT) to determine prevalence of leishmanial antibody. The rate varied from 2.9% to 14.1% among the different localities. The overall DAT positivity was 8.4%.Leishmanin Skin Test (LST) was used to determine exposure, with rate varied from 6.2% to 28.6% and with 12.3% over all prevalence. The difference in leishmanin positivity by study sites and sero prevalence by sex were all statistically significant (x2=67.59; P <0.01 and x 2 =14.76; P<0.05 respectively). Out of sero positive individuals 7 were young children (<5 years), who had no history of travel out of Bira Abo, suggesting that transmission occurred in the study site. Hence, there is a need to implement a sound control program. positive for M. bovis. The results indicated that M. tuberculosis is the causative species for tuberculous lymphadenitis in Dera.

Item Type: Thesis (Masters)
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Africana
Depositing User: Emmanuel Ndorimana
Date Deposited: 19 Nov 2018 09:25
Last Modified: 19 Nov 2018 09:25
URI: http://thesisbank.jhia.ac.ke/id/eprint/7503

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