Sabir, Anwar (2013) Magnitude of Anteretroviral Therapy Adherence and Associated Factors among Health Centers in Akaki Kality Subcity, AA, Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
Background The number of people living with HIV worldwide continued to grow in 2012, reaching an estimated 34million .Sub-Saharan Africa remains the region most heavily affected by HIV, In Ethiopia, the ART program started with a fee-based in 2003 then decentralized and free ART program in the Country was lunched since 2005. Non-adherence to the proposed antiretroviral regimen is considered to be one of the greatest dangers to the response to treatment. Objective The main objective of this study is to determine the antiretroviral treatment adherence and its associated factors among patients living with HIV/AIDS on combination antiretroviral therapy. Methodology: This is an institutional based cross sectional study. The study was conducted in Akaki kality sub city (Addis Ababa) from May to July. The study participants were selected by using systemic random sampling technique. Data was collected in three health center that is giving ART service. Of Total of 2698 client 633 client whom currently on ART follow up was sample study. Data was coded and entered in to Epi-info version 3.5.1and exported to SPSS version 20 for analysis. Descriptive statistics was used to generate proportion and odd ratio and confidence interval were calculated to assess the strength of associations of factors with adherence. logistic regression analysis was used to adjust or control the effect of different factor. Results: 88% percent of patients were adherent by self report in the month before the assessment.12% percent of patients were non adherent by self report The major reasons reported for non-adherence were, Twenty one percent of patients asserted that they missed their doses due to being away from home or having simply forgotten; while19.7% listed run out of medication as the primary reason for treatment non-adherence. Other barriers to treatment included: being sick (15.8%),being busy (11.8%),went holly water (9.2%), being depressed (7.9%),self problem in taking medication(6.6%),being sleep (5.3%),work load(3.9%), confusion about dosage direction(3.9%) , fear of disclosure(2.6%), too many pills(1.3%),toxicity of the drug(1.3%), taking a drug remind me of my HIV(1.3%),people told the medicine is not good(1.3%) . Associated factors of adherence in the multivariate analysis controlling for independent variable were: not being depressed, education, having social support and being closer to home from institution during follow up. Conclusions The adherence rates found in this study are comparable to those of other studies in developing countries but these rates are still low for good clinical outcomes. Since adherence is a dynamic process and patient’s behavior can change over time, there is also a need to have a follow up design, which would yield a more valid average measure of adherence as well as its determinants than a cross-sectional self-reported adherence assessment. Programs and clinical efforts to improve medication taking in the study setups should strive to manage depression with a multidisciplinary approach, Educational programme should be developed focusing on the people living with HIV-Aids.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Emmanuel Ndorimana |
| Date Deposited: | 28 Nov 2018 11:04 |
| Last Modified: | 28 Nov 2018 11:04 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/7877 |
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