Tiroro, Sisay (2015) The Magnitude and Associated Factors of Tuberculosis among Diabetic Patients at Tikur Anbessa Specialized Teaching Hospital in Addis Ababa, Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
Background: - Tuberculosis is a chronic infectious disease caused by the bacillus Mycobacterium tuberculosis, and it is a major cause of morbidity and mortality throughout the world. The link between tuberculosis and chronic diseases particularly diabetes mellitus have long recognized but underappreciated connection between the two revealing that diabetes makes substantial contribution to the burden of both incidence and prevalence of tuberculosis at the world wide level. People with diabetes have more than three times higher risk of developing active tuberculosis than people without diabetes. However, still there are a few studies on the burden of tuberculosis among diabetic patients in Ethiopia, particularly at Tikur Anbessa Specialized Teaching Hospital. Therefore, this study aimed to assess the magnitude and associated factors of tuberculosis among diabetic patients at Tikur Anbessa Specialized Teaching Hospital in Addis Ababa, Ethiopia. Objective: - To assess the magnitude and factors associated with tuberculosis among diabetic patients in Tikur Anbessa Specialized Teaching Hospital in Addis Ababa, Ethiopia. Methods: - Retrospective study was conducted at Tikur Anbessa Specialized Teaching Hospital in Addis Ababa, Ethiopia, from January 2010-January 2014. A total of six hundred eight one known diabetic patients aged ≥ 18 years were included in the study. Data was collected using checklist. Data were analyzed using SPSS for window version 20. Descriptive statistics such as frequency, proportions, means, medians and standard deviations were calculated. A binary logistic regression model was used to identify associated factors of tuberculosis among diabetic groups. The results were expressed by using adjusted odds ratio with 95% confidence interval a significant threshold was considered at p < 0.05. Results: - The magnitude of tuberculosis among diabetic populations was 3.8%, 95%CI (2.5%-5.3%). Age from 51-65 years (AOR=21.4; 95%CI; 1.2-385) , type-I diabetes mellitus (AOR=7;95%CI: 1.1-41.6) and age over 66 years (AOR=51; 95%CI: 3-877), body mass index less than 18 kg/m2 (AOR=27.6; 95%CI: 1.7-442), and prolonged duration of DM (AOR=5.1; 95%CI: 1-24) were significantly associated factors of tuberculosis among diabetic patients. Conclusion and recommendations: - In this study higher magnitude of tuberculosis was reported compared to other studies in developing countries. Age, low body mass index, type of diabetes mellitus and duration of diabetes were the significantly associated factors leading to occurrence of tuberculosis among diabetic patients. All diabetic patients should be screened for tuberculosis at their diagnosis time and they have regular follow up, and it is better to conduct further large scale epidemiological studies with large sample size and advanced tuberculosis diagnostic technologies.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Emmanuel Ndorimana |
| Date Deposited: | 10 Aug 2018 11:33 |
| Last Modified: | 10 Aug 2018 11:33 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/8041 |
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