Hailu, Tesfaye (2011) Pregnancy Outcomes in HIV Infected and Uninfected Women Attending ANC/PMTCT in Mekelle Town, Tigray Regional State, Ethiopia. Masters thesis, Addis Ababa University.
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Abstract
Background : Birth weight is a powerful predictor of infant survival, growth, long-term health and psychosocial development. Low birth weight has been defined by the World Health Organization (WHO) as weight at birth of less than 2,500 grams. Low birth weight (LBW) is a risk factor for infant mortality, morbidity, growth retardation, poor cognitive development and chronic diseases later in life.HIV infection during pregnancy may have a negative effect on birth weight, preterm birth and still birth. OBJECTIVE : the main objective of this study is to determine the effect of HIV infection on birth outcome. METHODOLOGY: Health facility based comparative cross sectional study was conducted to detrmine the effect of HIV infection on birth outcomes. A pretested data collection form was used to extract data from records of systematically selected pregnant women and their birth outcomes. Data was entered and validated using Epi -Info 3.5.1 for windows. Statistical analysis was performed using SPSS version 16 for windows. Bivariate analysis using student’s t-test was performed to compare means of continuous variables . Differences in proportions was analyzed using the chi-square test . Ethical clearance was obtained from the ethical review committe of the school of public health(SPH) and institutional review board(IRB) of College of Health Science of Addis Ababa University. RESULT: A total number of 711 pregnant women, 237 (33.3%) HIV infected and 474 (66.7%) HIV uninfected and their newborn characteristics was extracted from ANC and delivery registers and analyzed. The overall LBW rate was 11.7%% while mean birth weight was 2953+20.98(SE). Mean birth weight tend to be lower in infants born to HIV infected women compared to HIV uninfected women (2724.78 + 41 grams VS 3064.55 + 22 grams , independent t test , P<0.001). HIV infected women were more likely to have preterm births (OR = 1.534, 95% CI; 1.046, 2.249). Although not statistically significant , HIV infected women had higher proportion of still births (3.4%) compared to HIV uninfected women (1.9%) (X2 =1.47, P = 0.23). CONCLUSION AND RECOMENDATION: HIV infected pregnant women are at increased risk for preterm birth and lowbirth weight. Therefore, we suggest promoting of HIV infection among reproductive age group.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Emmanuel Ndorimana |
| Date Deposited: | 09 Aug 2018 11:47 |
| Last Modified: | 09 Aug 2018 11:47 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/8198 |
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