Fenta, Atnafu Temesgen (2016) Prevalence of HIV- Co Infection and Multiple Drug Resistance of Pulmonary Tuberculosis among Patients Attending Debre Markos Referral Hospital, Ethiopia. Masters thesis, Addis Ababa University.
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PDF (Prevalence of HIV – Co-Infection and Multiple Drug Resistance of Pulmonary Tuberculosis among Patients Attending Debre Markos Referral Hospital, Ethiopia)
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Abstract
Tuberculosis is a wide spread infectious disease caused by Mycobacterium tuberculosis which typically attack the lungs. There is a close association of tuberculosis (TB) infection with human immunodeficiency virus (HIV) co-infection. This, together with multiple drug resistance of the pathogen, makes it very difficult to control. This necessitates a survey of TB, multiple drug resistance and HIV co-infection on outpatients in order to evaluate the status and control of the disease. The main objective of the study was to assess the prevalence, HIV co-infection and multi drug resistance(MDR) of pulmonary tuberculosis among patients attending Debremarkos referral hospital. Descriptive cross sectional study design was conducted to investigate pulmonary tuberculosis (PTB) burden in the study site on secondary data source from recorded cases with complete socio demographic information. Data were analyzed using SPSS version 20 software. The study period was from January 2011- December 2015. From a total of 2886 PTB patients 1722 (59.7%) were males and 1164 (40.3%) were females. PTB decreased in the recent three years (2013, 2014 and 2015)compared with the previous two years (2011 and 2012). The burden of PTB was also high in 16-30 age groups (44.3%) than the other age groups such as the above 60 age groups (4.9%). In addition 84.8% were from rural area and 15.2% from urban dwellers. PTB decreased by 7.58% in the recent three years (2013, 2014,and,2015) than in (2011and 2012).The prevalence of HIV/PTB co infection among PTB cases was 18.8%. Co infection was highin males, and the same in active age groups of 16-30, rural area, and smear negative TB cases than the other groups. The trends of co infection decreased from 5.9% (2011) to 2.0% (2015). The prevalence of MDR-TB was 2.3%. Most MDR-TB cases were observed in males, 16-30 age groups and rural dwellers. Previous treatment showed strong association with the emergence of MDR-TB. The trend of MDR-TB was rapidly increasing from 0.0% to 0.9% across 2011- 2015 that needs to be addressed urgently.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | assessment, DOTS, PTB, secondary data |
| Subjects: | Q Science > Q Science (General) Q Science > QH Natural history > QH301 Biology R Medicine > RA Public aspects of medicine R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Selom Ghislain |
| Date Deposited: | 07 Sep 2018 06:55 |
| Last Modified: | 07 Sep 2018 06:55 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/4987 |
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