Zewdie, Berhan (2008) Synthesis and Antimicrobial Activity of Triphenyltinbenzoate Aniline Complex. Masters thesis, Addis Ababa University.
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Abstract
Triphenyltinbenzoate and triphenyltinbenzoate aniline complex had been synthesized and characterized on the basis of infrared, mass and nuclear magnetic resonance (1H and 13C) spectral studies. The synthesized compounds had sharp melting point which indicated the purity of the compounds. The antimicrobial activities of the synthesized compounds were tested against six different pathogenic microorganisms; Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Aspergillus niger and Candida ablicans in vitro. The results indicated that the synthesized compounds exhibit a higher activity against Escherichia coli, Streptococcus pyogenes, Pseudomonas aeruginosa and Candida ablicans than the starting compound. The results also indicated that the compounds did not exhibit any activity against Aspergillus niger at concentration as high as 200 µgml-1.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | Africana |
| Depositing User: | Selom Ghislain |
| Date Deposited: | 18 Sep 2018 09:13 |
| Last Modified: | 18 Sep 2018 09:13 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/5275 |
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