Study of Prevalence of Opportunistic Infections among HIV/AIDS Patients in Addis Ababa Public Hospitals

Beshah, Gedlu (2011) Study of Prevalence of Opportunistic Infections among HIV/AIDS Patients in Addis Ababa Public Hospitals. Masters thesis, Addis Ababa University.

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Abstract

Introduction: - The end result of HIV/ AIDS infection is the depletion of the immune system leading to a spectrum of various HIV/ AIDS associated opportunistic infections. Tuberculosis chronic and acute diarrhea of protozoal and bacterial infections, central nervous system infections with toxoplasma Gondi is the leading causes of morbidity and mortality in HIV/ AIDS infected patents. Objective: To describe the prevalence of opportunistic infection among HIV/AIDS patients and to identify socio-demographic factors for the development of severe forms namely central nervous system toxoplasmosis, pneumocysitc carrini pneumonia in the antiretro viral therapy clinics of public hospitals in Addis Ababa. Methods: A cross sectional study design on clinical records of HIV/AIDS patients in ART clinics. Systematic random sampling method was used to obtain the required sample. The total sample size was 566 Result: Oral candidacies 326(58. 0 %), Tuberculosis of all forms 260 (45.9%) and herpes zoster 198 (35%) had the highest prevalence. Therefore the prevalence of sever forms of the opportunistic infections made up 17.7% of the total sample. Using binary logistic regression model, WHO stage IV had an independent association with the distribution of the sever forms of the opportunistic infections. The odds of having the sever forms of the opportunistic infections was 40 times higher in the respondents who were in stage IV condition than stage III or II combined. The distribution of the sever form of opportunistic infections in St. Peter’s hospital was lower by 85% as compared to the referent hospital. There was no difference in the distribution of the sever forms of the opportunistic infections in the other 7 hospitals. There was also no difference in the distribution of the sever forms of the opportunistic infections among the socio demographic group of the age, sex, marital status and education. Conclusion: Oral candidacies, TB of all forms and herpes zoster were the predominant OIS. Only WHO stage IV condition and patients from St. Peters hospital were associated with the distribution of sever forms of the OIs. Recommendation: Skilled professionals for the management of the OIs and the implementation of the TB and HIV collaborative activities are of critical importance.

Item Type: Thesis (Masters)
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Africana
Depositing User: Emmanuel Ndorimana
Date Deposited: 04 Oct 2018 11:31
Last Modified: 04 Oct 2018 11:31
URI: http://thesisbank.jhia.ac.ke/id/eprint/5914

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