Mogessie, Yeshitila (2014) Epidemiology Training Program (EFETP). Masters thesis, Addis Ababa University.
![[img]](http://thesisbank.jhia.ac.ke/style/images/fileicons/application_pdf.png) |
PDF (Epidemiology Training Program (EFETP))
Final BOW -06-02-2014 by yeshitila.pdf - Accepted Version Restricted to Repository staff only Download (3MB) | Request a copy |
Abstract
Background: In Ethiopia meningococcal meningitis epidemics occur cyclically every three to five years in several regions that are located within the African meningitis belt. In January 2013 Hawassa City Administration reported an increase in persons with fever, headache, and vomiting and neck stiffness. We investigated to confirm the outbreak, identify risk factors and implement control measures. Methods: We defined a suspect case of meningococcal meningitis as any person with sudden onset of fever, vomiting and neck stiffness in Hawassa City from 22January-17 February 2013. We did active case surveillance for suspected cases from Addare and Referral Hospitals and collected CSF specimens from cases .We used Gram stain, latex agglutination and culture for confirming tests. We performed a case control study and compared meningococcal meningitis cases with their controls. We included all admitted cases that a physician diagnosed as meningococcal meningitis. Result: We identified 87 suspected cases and 4 deaths with CFR of 4.6%. The overall attack rate was 26/ 100,000 and age specific attack rate was highest among persons aged 15-29 years (ASAR 37.5/100,000). We isolated Serogroup, A, C, and W135, and gram negative diplococcus, from 8 CSF specimens. The index case admitted on 22th January from Philadelphia kebele. We declared the outbreak on 28th January. The peak case load was on week 6 and lasted through week 11 of 2013. Out of 27 cases and 54 controls having a history of recent past ten days acute respiratory infection significantly associated with contracting meningococcal meningitis {AOR= 4.7, 95% CI(1.5-14.9) }. Living in a room with a family size of four and above was significantly associated with the disease {AOR=4.5, 95% confidence interval (1.005-20.6)}. Conclusion: This investigation confirmed an outbreak of meningococcal meningitis and identified recent acute respiratory infection and overcrowded housing as significant risk factors Yeshitila Mogessie EFETP cohort IV Resident / 2014 Page 2 for contracting meningococcal meningitis. We can reduce the risk though community educating on reduction of overcrowding and respiratory infections. We recommended serogroup survey especially on w135 which help in the selection of vaccine type for mass vaccination in SNNPR.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Africana |
| Depositing User: | Vincent Mpoza |
| Date Deposited: | 01 Nov 2018 09:06 |
| Last Modified: | 01 Nov 2018 09:06 |
| URI: | http://thesisbank.jhia.ac.ke/id/eprint/7237 |
Actions (login required)
 |
View Item |